Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15692617 | 0.75 | KDM4E (0.39) | KAT2BKMT2AKDM4EALDH1A1 | |
| SCHEMBL16516540 | 0.73 | L3MBTL1 (0.44) | L3MBTL1KMT2AHTR2ANQO2KDM4E | |
| SCHEMBL28327541 | 0.73 | HTR2A (0.48) | L3MBTL1KMT2AHTR2ANQO2KDM4E | |
| SCHEMBL14693670 | 0.73 | L3MBTL1 (0.44) | L3MBTL1KMT2AHTR2ANQO2KDM4E | |
| SCHEMBL16008667 | 0.73 | L3MBTL1 (0.44) | L3MBTL1KMT2AHTR2ANQO2KDM4E | |
| SCHEMBL13591064 | 0.73 | HTR2A (0.48) | L3MBTL1KAT2BKMT2AHTR2AKDM4E | |
| SCHEMBL28328752 | 0.73 | L3MBTL1 (0.44) | L3MBTL1KMT2AHTR2ANQO2KDM4E | |
| SCHEMBL28363469 | 0.73 | KMT2A (0.43) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL10527114 | 0.69 | L3MBTL1 (0.40) | L3MBTL1KMT2AHTR2ANQO2KDM4E | |
| SCHEMBL30326110 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651820-A | Urea compounds for dual IDO and TDO inhibitors | 正大天晴药业集团股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-110382500-B | Urea compounds for dual IDO and TDO inhibitors | 正大天晴药业集团股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-110382500-A | Carbamide compounds for IDO and TDO double inhibitor | 正大天晴药业集团股份有限公司 | 2019-10-25 | — | — | CN | disclosed |