Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16516540 | 0.81 | L3MBTL1 (0.44) | L3MBTL1KMT2AALDH1A1HIF1ACYP1B1 | |
| SCHEMBL16008667 | 0.81 | L3MBTL1 (0.44) | L3MBTL1KMT2AALDH1A1HIF1ACYP1B1 | |
| SCHEMBL14693670 | 0.81 | L3MBTL1 (0.44) | L3MBTL1KMT2AALDH1A1HIF1ACYP1B1 | |
| SCHEMBL28327541 | 0.81 | HTR2A (0.48) | L3MBTL1KMT2AALDH1A1HIF1ACYP1B1 | |
| SCHEMBL9494876 | 0.80 | ADORA3 (0.45) | L3MBTL1ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL31427619 | 0.78 | ALDH1A1 (0.37) | L3MBTL1KMT2AALDH1A1HIF1ACYP1B1 | |
| SCHEMBL10527114 | 0.77 | L3MBTL1 (0.40) | L3MBTL1KMT2AALDH1A1HIF1ACYP1B1 | |
| SCHEMBL27599861 | 0.77 | L3MBTL1 (0.40) | L3MBTL1KMT2AALDH1A1NQO2KDM4E | |
| Bromide SCHEMBL5045247 | 0.76 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1HIF1ACYP1B1HSD17B10 | |
| SCHEMBL28457078 | 0.75 | MAPK1 (0.51) | ALDH1A1KDM4ECYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651820-A | Urea compounds for dual IDO and TDO inhibitors | 正大天晴药业集团股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-110382500-B | Urea compounds for dual IDO and TDO inhibitors | 正大天晴药业集团股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-110382500-A | Carbamide compounds for IDO and TDO double inhibitor | 正大天晴药业集团股份有限公司 | 2019-10-25 | — | — | CN | disclosed |