Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYCS | P99999 | 4/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 2/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30831213 | 1.00 | CYCS (0.38) | CYCSMMP12MEN1KMT2AABCG2 | |
| SCHEMBL28675072 | 0.91 | CYCS (0.35) | CYCSMEN1KMT2AABCG2TOP1 | |
| SCHEMBL30831231 | 0.91 | CYCS (0.35) | CYCSMEN1KMT2AABCG2TOP1 | |
| SCHEMBL28671051 | 0.90 | USP2 (0.35) | CYCSMEN1KMT2ATOP1POLB | |
| SCHEMBL30831219 | 0.90 | USP2 (0.35) | CYCSMEN1KMT2ATOP1POLB | |
| SCHEMBL28672575 | 0.89 | CYCS (0.38) | CYCSMMP12MEN1KMT2AABCG2 | |
| SCHEMBL28669582 | 0.83 | CYCS (0.47) | CYCSMMP12ABCG2TOP1 | |
| SCHEMBL28680667 | 0.81 | CTSA (0.36) | CYCSMEN1KMT2ATOP1POLB | |
| SCHEMBL28693629 | 0.80 | USP2 (0.35) | CYCSMEN1KMT2ATOP1USP2 | |
| SCHEMBL9369158 | 0.77 | LMNA (0.46) | CYCSMEN1KMT2ATOP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | disclosed |