Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 7/20 | 0.36 |
| ▸ | METAP1 | P53582 | 6/20 | 0.36 |
| ▸ | CAD | P27708 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3020789 | 0.83 | ALOX15 (0.48) | ALOX15ALDH1A1LMNAHSD17B10CPB2 | |
| Hydrochloric Acid SCHEMBL18230686 | 0.81 | ALOX15 (0.46) | ALOX15ALDH1A1LMNAHSD17B10CPB2 | |
| SCHEMBL819368 | 0.81 | ALDH1A1 (0.43) | ALOX15ALDH1A1LMNAHSD17B10CPB2 | |
| Hydrochloric Acid SCHEMBL18230685 | 0.81 | ALOX15 (0.46) | ALOX15ALDH1A1LMNAHSD17B10CPB2 | |
| SCHEMBL1532549 | 0.81 | SOAT1 (0.46) | ALOX15ALDH1A1LMNAHSD17B10CPB2 | |
| SCHEMBL19318891 | 0.80 | ALDH1A1 (0.53) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL12640198 | 0.80 | ALDH1A1 (0.53) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL13309535 | 0.78 | — | — | |
| SCHEMBL10681632 | 0.77 | ALOX15 (0.42) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL11379632 | 0.76 | ALOX15 (0.41) | ALOX15ALDH1A1LMNAHSD17B10CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108738320-B | cGMP modulators for the treatment of cardiovascular diseases | 默沙东公司 | 2021-11-19 | — | — | CN | disclosed |