SCHEMBL28670346

SCHEMBL28670346

CCCCC(F)(F)C(=O)ON

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.47
FAAH O00519 8/20 0.38
CES1 P23141 7/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 1/20 0.36
HSD17B10 Q99714 1/20 0.36
FDPS P14324 1/20 0.36
LPAR1 Q92633 1/20 0.34
LPAR3 Q9UBY5 1/20 0.34
EPHX1 P07099 1/20 0.33
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10970451 0.81 CES2 (0.48) CES2FAAHCES1MEN1KMT2A
SCHEMBL2880832 0.81 CES2 (0.53) CES2FAAHCES1MEN1KMT2A
SCHEMBL1619413 0.79 CES2 (0.47) CES2FAAHCES1MEN1KMT2A
SCHEMBL29077638 0.78 CES2 (0.46) CES2FAAHCES1MEN1KMT2A
SCHEMBL8657187 0.77 FDPS (0.42) CES2FAAHCES1MEN1KMT2A
SCHEMBL11534492 0.75 CES2 (0.57) CES2FAAHCES1MEN1KMT2A
SCHEMBL11795301 0.73 CES2 (0.60) CES2FAAHCES1MEN1KMT2A
SCHEMBL11288151 0.73 CES2 (0.60) CES2FAAHCES1MEN1KMT2A
SCHEMBL21802245 0.73 CES2 (0.66) CES2FAAHCES1MEN1KMT2A
SCHEMBL15059581 0.73 CES2 (0.55) CES2FAAHCES1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109999856-B Catalyst for synthesizing 2, 2-difluoroethylamine and preparation method and application thereof 陕西神光化学工业有限公司 2021-11-30 CN disclosed