Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030721 | 0.89 | MAPT (0.59) | GAATSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13486817 | 0.83 | GAA (0.69) | GAATSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5236125 | 0.83 | GAA (0.52) | GAATSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2153429 | 0.82 | ALDH1A1 (0.52) | TSHRALDH1A1CYP1A2L3MBTL1KMT2A | |
| SCHEMBL456580 | 0.80 | ALDH1A1 (0.69) | GAATSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27680096 | 0.79 | GAA (0.52) | GAATSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1424233 | 0.79 | GAA (0.47) | GAATSHRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8720110 | 0.77 | CHEK1 (0.65) | GAATSHRMAPTALDH1A1HTT | |
| SCHEMBL28788237 | 0.75 | CNR2 (0.49) | GAATSHRHTTCA2CHEK1 | |
| SCHEMBL11552289 | 0.75 | ALDH1A1 (0.54) | GAATSHRMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115626894-B | Lappaconitine derivative with analgesic activity, and preparation method and application thereof | 西南交通大学 | 2025-04-18 | — | — | CN | disclosed |
| CN-115626894-A | Lappaconitine derivative with analgesic activity and preparation method and application thereof | 西南交通大学 | 2023-01-20 | — | — | CN | disclosed |
| CN-113105391-B | Lappaconitine derivative with analgesic activity and preparation method and application thereof | 西南交通大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-113105391-A | Lappaconitine derivative with analgesic activity and preparation method and application thereof | 西南交通大学 | 2021-07-13 | — | — | CN | disclosed |