Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680096 | 0.86 | GAA (0.52) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL10732973 | 0.82 | MAPT (0.61) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL1227388 | 0.82 | MAPT (1.00) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL12506468 | 0.82 | MAPT (0.75) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL13066504 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL28670522 | 0.80 | GAA (0.50) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL29414291 | 0.80 | GAA (0.95) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL9175776 | 0.80 | MAPT (0.72) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL4213821 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MAPTGAASMN1; SMN2TSHR | |
| SCHEMBL15240 | 0.80 | ALDH1A1 (0.72) | ALDH1A1MAPTGAASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116376009-A | Water-based low-migration diphenyl ketone photoinitiator and preparation method thereof | 万华化学集团股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-108440389-B | 3,4, 5-trihydroxybenzoic acid derivative and preparation method and application thereof | 山东大学 | 2020-05-29 | — | — | CN | claimed |
| CN-105367436-A | Preparation method of N,N-dimethyl benzoate composite | TIANJIN JIURI NEW MAT CO LTD | 2016-03-02 | — | — | CN | claimed |
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | claimed |
| WO-2014059436-A1 | ELECTRONIC TUNING OF SITE SELECTIVITY | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-04-17 | — | — | WO | claimed |
| CN-102659956-B | Modified ultraviolet absorbing agent based on araboxylan and preparation method thereof | UNIV JIANGNAN | 2013-10-30 | — | — | CN | claimed |
| CN-102198053-A | Synthesis and application of similar quaternized chitosan sunscreen | UNIV JIANGNAN | 2011-09-28 | — | — | CN | claimed |
| US-20250248990-A1 | QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE | NEURODON CORPORATION | 2025-08-07 | — | — | US | disclosed |
| US-12144806-B2 | Quinolines that modulate SERCA and their use for treating disease | NEURODON CORPORATION (US) | 2024-11-19 | — | — | US | disclosed |
| US-20240277694-A1 | QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE | NEURODON CORPORATION | 2024-08-22 | — | — | US | disclosed |
| CN-118256183-A | Quick plugging adhesive, preparation method and application | 中国石油天然气集团有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-11992487-B2 | Quinolines that modulate SERCA and their use for treating disease | NEURODON CORPORATION (US) | 2024-05-28 | — | — | US | disclosed |
| EP-4037685-B9 | QUINOLINE THAT MODULATE SERCA AND ITS USE FOR TREATING DISEASE | NEURODON CORP (US) | 2024-03-06 | — | — | EP | disclosed |
| EP-0284873-B1 | SILYLATION METHOD | GENERAL ELECTRIC COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-4968680-A | HYPOTENSIVE, ANTIEDEMIC, DIURETIC | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0363584-A2 | Silylation method | GENERAL ELECTRIC COMPANY (US) | 1990-04-18 | — | — | EP | disclosed |
| US-4918197-A | CATALYTIC REACTION BETWEEN AROMATIC ACYLHALIDE AND HALOGENATED POLYSILANE | GENERAL ELECTRIC COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0315115-A2 | 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives, process for producing them and use thereof | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-10 | — | — | EP | disclosed |
| EP-0284873-A2 | Silylation method | GENERAL ELECTRIC COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4709054-A | REACTION OF AROMATIC ACYL HALIDE AND HALOGENATED POLYSILANE, TRANSITION METAL CATALYST | GENERAL ELECTRIC COMPANY (US) | 1987-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11992487-B2 | Quinolines that modulate SERCA and their use for treating disease | ATP2A1, ATP2A3, ATP2A2 | ALDH1A1 1661/4885MAPT 1228/4885GAA 94/4885 |
| US-12144806-B2 | Quinolines that modulate SERCA and their use for treating disease | ATP2A1, ATP2A3, ATP2A2 | ALDH1A1 1661/4885MAPT 1228/4885GAA 94/4885 |
| US-20250248990-A1 | QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE | ATP2A1, ATP2A3, ATP2A2 | ALDH1A1 1661/4885MAPT 1228/4885GAA 94/4885 |
| US-20240277694-A1 | QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE | ATP2A1, ATP2A3, ATP2A2 | ALDH1A1 1661/4885MAPT 1228/4885GAA 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.