Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 10/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758953 | 1.00 | DRD2 (0.57) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL18215162 | 1.00 | DRD2 (0.57) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL21020862 | 0.94 | DRD2 (0.52) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL21020832 | 0.93 | CARM1 (0.51) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL27478660 | 0.93 | CARM1 (0.51) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL27478669 | 0.93 | CARM1 (0.51) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL18212444 | 0.91 | PRMT5 (0.51) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL28928597 | 0.91 | PRMT5 (0.51) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL29758947 | 0.91 | PRMT5 (0.51) | DRD2PRMT5WDR77POLBHDAC4 | |
| SCHEMBL9035931 | 0.85 | DRD2 (0.55) | DRD2PRMT5WDR77POLBCARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |