Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.55 |
| ▸ | PRMT5 | O14744 | 12/20 | 0.52 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035921 | 1.00 | DRD2 (0.55) | DRD2PRMT5WDR77CTSKPOLB | |
| SCHEMBL28670702 | 0.85 | DRD2 (0.57) | DRD2PRMT5WDR77CTSKPOLB | |
| SCHEMBL29758953 | 0.85 | DRD2 (0.57) | DRD2PRMT5WDR77CTSKPOLB | |
| SCHEMBL18215162 | 0.85 | DRD2 (0.57) | DRD2PRMT5WDR77CTSKPOLB | |
| SCHEMBL496318 | 0.81 | KLK5 (0.54) | DRD2PRMT5WDR77POLB | |
| SCHEMBL496319 | 0.81 | KLK5 (0.54) | DRD2PRMT5WDR77POLB | |
| SCHEMBL21020862 | 0.79 | DRD2 (0.52) | DRD2PRMT5WDR77CTSKPOLB | |
| SCHEMBL21020832 | 0.79 | CARM1 (0.51) | DRD2PRMT5WDR77CTSKPOLB | |
| SCHEMBL27478669 | 0.79 | CARM1 (0.51) | DRD2PRMT5WDR77CTSKPOLB | |
| SCHEMBL27478660 | 0.79 | CARM1 (0.51) | DRD2PRMT5WDR77CTSKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |