Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | FDPS | P14324 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28650607 | 0.98 | ADRA2A (0.37) | GRM5ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL23768088 | 0.79 | GRM5 (0.56) | GRM5NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL28664048 | 0.77 | GRM5 (0.35) | GRM5NPC1RAB9AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28654433 | 0.77 | GRM5 (0.54) | GRM5ADRA2AADRA2BADRA2CADRA1D | |
| Hydrochloric Acid SCHEMBL28664404 | 0.76 | GRM5 (0.34) | GRM5NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL10297562 | 0.75 | L3MBTL1 (0.34) | GRM5ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL27791995 | 0.74 | GRM5 (0.37) | GRM5NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL28658624 | 0.74 | HSD17B10 (0.38) | GRM5ADRA2AADRA2BADRA2CADRA1D | |
| SCHEMBL5700039 | 0.73 | TRIM24 (0.38) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL5700533 | 0.73 | SMN1; SMN2 (0.37) | GRM5ADRA2AADRA2BADRA2CADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991703-A | Ring-fused compound, preparation method thereof, pharmaceutical composition and application | 广州费米子科技有限责任公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-113717167-B | Fused ring compound, preparation method thereof, pharmaceutical composition and application | 广州费米子科技有限责任公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-113717167-A | Fused ring compound, preparation method thereof, pharmaceutical composition and application | 广州费米子科技有限责任公司 | 2021-11-30 | — | — | CN | disclosed |