Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16409996 | 0.80 | SIRT2 (1.00) | SIRT2MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL31160341 | 0.78 | SIRT2 (0.66) | SIRT2MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL29371599 | 0.77 | SIRT2 (0.59) | SIRT2MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL14426679 | 0.77 | SMN1; SMN2 (0.92) | SIRT2MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL28303339 | 0.77 | MAPT (0.56) | SIRT2MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL10960723 | 0.77 | ALDH1A1 (0.71) | SIRT2MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL4208096 | 0.73 | SMN1; SMN2 (0.66) | MAPTSMN1; SMN2GAAHPGDMAPK1 | |
| SCHEMBL31160373 | 0.72 | SIRT2 (0.60) | SIRT2MAPTSMN1; SMN2GAAHPGD | |
| SCHEMBL28693087 | 0.72 | ALDH1A1 (0.66) | GAAHPGDMAPK1ALDH1A1LMNA | |
| SCHEMBL5657358 | 0.71 | MAPT (0.63) | MAPTSMN1; SMN2ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970668-B | Method for preparing 3-thio-1, 2, 4-triazole compound | 普济生物科技（台州）有限公司 | 2021-12-07 | — | — | CN | disclosed |