Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22473247 | 1.00 | LMNA (0.44) | LMNAGPR119PRMT5WDR77ALDH1A1 | |
| SCHEMBL3261075 | 0.86 | PRMT5 (0.53) | LMNAGPR119PRMT5WDR77ALDH1A1 | |
| SCHEMBL30487081 | 0.84 | LMNA (0.59) | LMNAPRMT5WDR77ALDH1A1GAA | |
| SCHEMBL20164005 | 0.84 | LMNA (0.59) | LMNAPRMT5WDR77ALDH1A1GAA | |
| SCHEMBL8575615 | 0.84 | LMNA (0.59) | LMNAPRMT5WDR77ALDH1A1GAA | |
| SCHEMBL20528487 | 0.81 | SCD (0.46) | LMNAPRMT5WDR77ALDH1A1GAA | |
| SCHEMBL20449190 | 0.81 | SCD (0.46) | LMNAPRMT5WDR77ALDH1A1GAA | |
| SCHEMBL22473361 | 0.81 | PRMT5 (0.43) | LMNAPRMT5WDR77ALDH1A1GAA | |
| SCHEMBL30541398 | 0.81 | TSHR (0.43) | LMNAALDH1A1KMT2AL3MBTL1RIPK1 | |
| SCHEMBL30476145 | 0.81 | ALOX5AP (0.43) | LMNAALDH1A1KMT2AL3MBTL1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744929-A | Compounds and uses thereof | 福霍恩治疗公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-108290881-B | Therapeutic compounds and methods of use thereof | 健泰科生物技术公司 | 2021-12-07 | — | — | CN | disclosed |