Carbimide

Carbimide

SCHEMBL286710

CC(C)c1cc(C(C)C)cc(C(C)C)c1.CC(C)c1cc(C(C)C)cc(C(C)C)c1.N=C=N

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.39
GABRB2 P47870 1/20 0.39
FABP3 P05413 2/20 0.37
FABP4 P15090 2/20 0.37
FABP5 Q01469 1/20 0.36
LMNA P02545 1/20 0.35
TRPA1 O75762 1/20 0.33
PTGS1 P23219 1/20 0.33
CACNA1C Q13936 1/20 0.33
ALDH1A1 P00352 2/20 0.32
ALOX12 P18054 2/20 0.32
HTT P42858 2/20 0.32
GAA P10253 1/20 0.32
HIF1A Q16665 1/20 0.32
TYR P14679 2/20 0.31
GABRB1 P18505 1/20 0.31
RNASEH1 O60930 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MDM4 O15151 1/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbimide SCHEMBL17255549 1.00 GABRA1 (0.39) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL659373 0.88 FABP3 (0.39) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL338867 0.86 GABRA1 (0.46) GABRA1GABRB2FABP3FABP4FABP5
Carbimide SCHEMBL23877346 0.83 HDAC4 (0.48) LMNATRPA1PTGS1CACNA1CALDH1A1
Carbimide SCHEMBL17255508 0.83 HDAC4 (0.48) LMNATRPA1PTGS1CACNA1CALDH1A1
SCHEMBL3234036 0.82 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL23202734 0.82 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
Hydrochloric Acid SCHEMBL5790729 0.82 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
Calcium SCHEMBL29750665 0.82 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL23202783 0.82 GABRA1 (0.43) GABRA1GABRB2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9127098-B2 O-imino-iso-urea compounds and polymerizable compositions thereof BASF SE (DE) 2015-09-08 US disclosed
EP-2427428-B1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2015-08-19 EP disclosed
US-20140113987-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2014-04-24 US disclosed
US-8664288-B2 O-imino-iso-urea compounds and polymerizable compositions thereof BASF SE (DE) 2014-03-04 US disclosed
US-20120108696-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2012-05-03 US disclosed
EP-2427428-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2012-03-14 EP disclosed
WO-2010128062-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF BASF SE (DE) 2010-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108696-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF CCNC, CCNO, CCNI GABRA1 3753/4885GABRB2 3332/4885FABP3 1976/4885
US-20140113987-A1 O-IMINO-ISO-UREA COMPOUNDS AND POLYMERIZABLE COMPOSITIONS THEREOF CCNC, CPS1, ODC1 GABRA1 3813/4885GABRB2 3469/4885FABP3 2056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.