SCHEMBL2867115

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2862928	0.89	PIP5K1C (0.46)	PIP5K1CJAK2JAK3NPC1RAB9A
	SCHEMBL2861468	0.86	JAK2 (0.44)	JAK2JAK3MAOBSIRT2SIRT1
	SCHEMBL4346837	0.83	MKNK1 (0.46)	JAK2JAK3MAOBSIRT2SIRT1
	SCHEMBL2864933	0.82	PIP5K1C (0.48)	PIP5K1CJAK2JAK3NPC1RAB9A
	SCHEMBL4332228	0.82	HSD17B10 (0.46)	JAK2JAK3NPC1RAB9ATP53
	SCHEMBL13636099	0.82	TACR3 (0.40)	JAK2JAK3
	SCHEMBL4346677	0.82	TACR3 (0.40)	JAK2JAK3
	SCHEMBL2866722	0.79	GSK3B (0.41)	PIP5K1CJAK2JAK3SIRT2SIRT1
	SCHEMBL2857638	0.78	KDR (0.40)	JAK2JAK3NPC1RAB9AMAOB
	SCHEMBL4339195	0.78	SIRT2 (0.40)	PIP5K1CJAK2JAK3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.