SCHEMBL2864933

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2862928	0.86	PIP5K1C (0.46)	PIP5K1CNPC1RAB9AMAOBSIRT2
	SCHEMBL2872600	0.84	KDM4E (0.45)	PIP5K1CNPC1RAB9AMAOBSIRT2
	SCHEMBL4331298	0.83	KDM4E (0.42)	NPC1RAB9AMAOBSIRT2SIRT1
	SCHEMBL2867115	0.82	PIP5K1C (0.45)	PIP5K1CNPC1RAB9AMAOBSIRT2
	SCHEMBL2861587	0.81	KDR (0.49)	NPC1RAB9AKDRCHEK1GSK3B
	Cyclopropanecarboxylic Acid Amide SCHEMBL2864932	0.81	SIRT2 (0.48)	PIP5K1CNPC1RAB9AMAOBSIRT2
	SCHEMBL4341132	0.80	ALDH1A1 (0.41)	NPC1RAB9AMAOBSIRT2SIRT1
	SCHEMBL4341026	0.79	TSHR (0.41)	NPC1RAB9AMAOB
	SCHEMBL13198263	0.79	MKNK1 (0.48)	NPC1RAB9AMAOBSIRT2SIRT1
	SCHEMBL4334476	0.79	MKNK1 (0.48)	NPC1RAB9AMAOBSIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.