SCHEMBL2862928

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2867115	0.89	PIP5K1C (0.45)	PIP5K1CRAB9ANPC1MAOBSIRT2
	SCHEMBL4339195	0.88	SIRT2 (0.40)	PIP5K1CRAB9ANPC1MAOBSIRT2
	SCHEMBL2866722	0.88	GSK3B (0.41)	PIP5K1CSIRT2SIRT1JAK2JAK3
	SCHEMBL2864933	0.86	PIP5K1C (0.48)	PIP5K1CRAB9ANPC1MAOBSIRT2
	SCHEMBL2872405	0.85	MAPT (0.41)	MAOBSIRT2SIRT1KDRL3MBTL1
	SCHEMBL4334418	0.83	ALDH1A1 (0.54)	RAB9ANPC1KDM4EMEN1MAPT
	SCHEMBL4334565	0.83	LMNA (0.41)	JAK2JAK3KDM4EMEN1CYP1A2
	SCHEMBL4336829	0.82	KDM4E (0.43)	JAK2JAK3KDM4EMEN1MAPT
	SCHEMBL2864594	0.82	KDR (0.47)	RAB9ANPC1KDRPTK2L3MBTL1
	SCHEMBL4342246	0.82	MAOA (0.40)	RAB9AMAOBSIRT2SIRT1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.