Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867171 | 1.00 | TSHR (0.36) | TSHRALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL875951 | 0.84 | MAPT (0.38) | TSHRALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL10955082 | 0.84 | USP2 (0.35) | TSHRALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL5435517 | 0.83 | TSHR (0.33) | TSHRALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL14564236 | 0.81 | LMNA (0.36) | TSHRALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL5435503 | 0.81 | LMNA (0.36) | TSHRALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL5438123 | 0.77 | LMNA (0.36) | TSHRALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL5438132 | 0.77 | LMNA (0.36) | TSHRALDH1A1CYP3A4MAPTUSP2 | |
| SCHEMBL8909446 | 0.76 | LMNA (0.30) | LMNA | |
| SCHEMBL9346978 | 0.76 | LMNA (0.30) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003138-B1 | METHOD FOR PRODUCING ALDEHYDE USING BISPHOSPHITE AND GROUP 8-10 METAL COMPOUND, AND SUCH BISPHOSPHITE | KURARAY CO (JP) | 2013-10-09 | — | — | EP | claimed |
| CN-101415717-B | Method for producing aldehyde using bisphosphite and group 8-10 metal compound, and such bisphosphite | KURARAY CO | 2012-12-12 | — | — | CN | claimed |
| US-7745666-B2 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | KURARAY CO., LTD. (JP) | 2010-06-29 | — | — | US | claimed |
| US-20090259073-A1 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | KURARAY CO., LTD (JP) | 2009-10-15 | — | — | US | claimed |
| CN-101415717-A | Method for producing aldehyde using bisphosphite and group 8-10 metal compound, and such bisphosphite | KURARAY CO (JP) | 2009-04-22 | — | — | CN | claimed |
| US-7491850-B2 | Useful component of catalysts used in the hydroformylation of olefins with carbon monoxide and hydrogen; reaction under milder conditions | KURARAY CO., LTD. (JP) | 2009-02-17 | — | — | US | claimed |
| EP-2003138-A1 | METHOD FOR PRODUCING ALDEHYDE USING BISPHOSPHITE AND GROUP 8-10 METAL COMPOUND, AND SUCH BISPHOSPHITE | Kuraray Co., Ltd. (JP) | 2008-12-17 | — | — | EP | claimed |
| EP-2003138-B1 | METHOD FOR PRODUCING ALDEHYDE USING BISPHOSPHITE AND GROUP 8-10 METAL COMPOUND, AND SUCH BISPHOSPHITE | KURARAY CO (JP) | 2013-10-09 | — | — | EP | disclosed |
| CN-101415717-B | Method for producing aldehyde using bisphosphite and group 8-10 metal compound, and such bisphosphite | KURARAY CO | 2012-12-12 | — | — | CN | disclosed |
| US-7745666-B2 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | KURARAY CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| EP-1728796-B1 | BISPHOSPHITE AND PROCESS FOR PRODUCING ALDEHYDE COMPOUND WITH THE BISPHOSPHITE | KURARAY CO LTD KURASHIKI PLANT (JP) | 2010-03-17 | — | — | EP | disclosed |
| US-20090259073-A1 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | KURARAY CO., LTD (JP) | 2009-10-15 | — | — | US | disclosed |
| CN-101415717-A | Method for producing aldehyde using bisphosphite and group 8-10 metal compound, and such bisphosphite | KURARAY CO (JP) | 2009-04-22 | — | — | CN | disclosed |
| US-20050038273-A1 | Method for telomerizing non-cyclic olefins | OXENO OLEFINCHEMIE GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| US-5004568-A | Reacting With Carbon Monoxide Using A Group 8 Noble Metal Halide Catalyst And A Group 1B Metal Halide | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| US-4767574-A | CATALYTIC WITH GROUP 8 NOBLE METAL HALIDE AND HALIDE COMPOUND | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1988-08-30 | — | — | US | disclosed |
| US-4675435-A | CARBONYLATION OF ACYCLIC ALLYLIC ETHER | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0217407-A2 | Carbonylation of allylic ethers to esters | QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) | 1987-04-08 | — | — | EP | disclosed |
| US-4622416-A | GROUP 8 HALIDE CATALYSTS | NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) | 1986-11-11 | — | — | US | disclosed |
| US-4146738-A | ACTIVATED PALLADIUM TRIARYLPHOSPHINE CATALYST | CHEMISCHE WERKE HUELS, AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259073-A1 | Rreacting a nonconjugated diene having a double bond in an end and having from 6-20 carbon atoms with a carbon monoxide and hydrogen in the presence of a bisphosphite and a transition metal compound to provide an unsaturated acyclic aldehyde; | CBR1, RCN1, CYC1 | TSHR 1996/4885ALDH1A1 72/4885CYP3A4 436/4885 |
| US-20050038273-A1 | Method for telomerizing non-cyclic olefins | PCNA, TELO2, TTI1 | TSHR 3017/4885ALDH1A1 3141/4885CYP3A4 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.