Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286261 | 1.00 | GABRA1 (0.46) | GABRA1KMT2A | |
| SCHEMBL286575 | 1.00 | GABRA1 (0.46) | GABRA1KMT2A | |
| SCHEMBL287021 | 0.87 | GABRA1 (0.59) | GABRA1 | |
| SCHEMBL286449 | 0.86 | GABRA1 (0.48) | GABRA1 | |
| SCHEMBL286650 | 0.86 | GABRA1 (0.48) | GABRA1 | |
| SCHEMBL286795 | 0.84 | GABRA1 (0.48) | GABRA1 | |
| SCHEMBL286586 | 0.83 | GABRA1 (0.62) | GABRA1 | |
| SCHEMBL286582 | 0.82 | KMT2A (0.38) | GABRA1KMT2A | |
| SCHEMBL286328 | 0.82 | KMT2A (0.38) | GABRA1KMT2A | |
| SCHEMBL286574 | 0.80 | GABRA1 (0.54) | GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427458-A1 | ISOXAZOLE-PYRIDAZINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |