Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 7/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672294 | 1.00 | FLT3 (0.52) | FLT3CYP3A4HPGDCNR1CNR2 | |
| SCHEMBL28660083 | 0.89 | PTGES (0.51) | FLT3CNR1CNR2PTGES | |
| SCHEMBL28660085 | 0.89 | PTGES (0.51) | FLT3CNR1CNR2PTGES | |
| SCHEMBL28658973 | 0.88 | CNR1 (0.47) | CYP3A4CNR1CNR2FAAHEPHX2 | |
| SCHEMBL28658975 | 0.88 | CNR1 (0.47) | CYP3A4CNR1CNR2FAAHEPHX2 | |
| SCHEMBL16191696 | 0.84 | FLT3 (0.58) | FLT3CYP3A4HPGD | |
| SCHEMBL16191700 | 0.84 | FLT3 (0.58) | FLT3CYP3A4HPGD | |
| SCHEMBL28890292 | 0.79 | CYP3A4 (0.50) | FLT3CYP3A4HPGD | |
| SCHEMBL28656810 | 0.79 | TDP1 (0.51) | FLT3CYP3A4HPGD | |
| SCHEMBL30358568 | 0.79 | TDP1 (0.51) | FLT3CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116270577-A | Application of polysubstituted benzene compounds in preparation of medicines for treating cognitive impairment diseases, structure and preparation method | 中国医学科学院医药生物技术研究所 | 2023-06-23 | — | — | CN | disclosed |
| CN-116270576-A | Application of polysubstituted benzene compounds in preparation of medicines for treating cognitive impairment diseases, structure and preparation method | 中国医学科学院医药生物技术研究所 | 2023-06-23 | — | — | CN | disclosed |
| CN-113521048-B | Application of polysubstituted benzene compound in preparation of medicine for treating cognitive disorder diseases, structure and preparation method | 中国医学科学院医药生物技术研究所 | 2023-04-14 | — | — | CN | disclosed |
| CN-113521048-A | Application of polysubstituted benzene compound in preparation of medicine for treating cognitive disorder diseases, structure and preparation method | 中国医学科学院医药生物技术研究所 | 2021-10-22 | — | — | CN | disclosed |