Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688377 | 0.89 | MAPK1 (0.46) | L3MBTL1TSHRPOLBMAPK1KMT2A | |
| SCHEMBL11033321 | 0.85 | POLB (0.44) | L3MBTL1TSHRPOLBMAPK1KMT2A | |
| SCHEMBL10926531 | 0.85 | POLB (0.44) | L3MBTL1TSHRPOLBMAPK1KMT2A | |
| SCHEMBL27641736 | 0.83 | KMT2A (0.43) | L3MBTL1POLBMAPK1KMT2ARAB9A | |
| SCHEMBL27676369 | 0.83 | KMT2A (0.51) | L3MBTL1KMT2ARAB9AMEN1TDP1 | |
| SCHEMBL10926562 | 0.83 | FAAH (0.44) | L3MBTL1TSHRPOLBMAPK1KMT2A | |
| SCHEMBL11035609 | 0.83 | POLB (0.42) | L3MBTL1TSHRPOLBMAPK1KMT2A | |
| SCHEMBL28393952 | 0.82 | L3MBTL1 (0.65) | L3MBTL1POLBKMT2ARAB9AMEN1 | |
| SCHEMBL10926617 | 0.82 | FAAH (0.43) | L3MBTL1TSHRPOLBMAPK1KMT2A | |
| SCHEMBL10926539 | 0.82 | FAAH (0.43) | L3MBTL1TSHRPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861072-A | Preparation method of aryl cyclopropane compound | 上海麦克林生化科技有限公司 | 2021-12-31 | — | — | CN | disclosed |