Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | CASP3 | P42574 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30494363 | 1.00 | MAPT (0.69) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL30494359 | 0.83 | MAPT (0.75) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL28675538 | 0.83 | MAPT (0.75) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL29633257 | 0.82 | MAPT (1.00) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL754259 | 0.82 | MAPT (1.00) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL16296882 | 0.82 | MAPT (0.69) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL16296863 | 0.82 | MAPT (0.69) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL29746447 | 0.82 | MAPT (0.69) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL30991489 | 0.82 | MAPT (0.69) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL29633296 | 0.82 | MAPT (0.69) | MAPTRAB9ALMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113666887-B | 1, 4-naphthoquinone derivative, synthesis method and application | 江苏海洋大学 | 2023-07-28 | — | — | CN | disclosed |
| CN-113666887-A | 1, 4-naphthoquinone derivative, and synthesis method and application thereof | 江苏海洋大学 | 2021-11-19 | — | — | CN | disclosed |