SCHEMBL754259

SCHEMBL754259

O=C1C=C(Nc2ccccc2)C(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
SMN1; SMN2 Q16637 6/20 1.00
RAB9A P51151 5/20 1.00
MAPK1 P28482 5/20 1.00
L3MBTL1 Q9Y468 5/20 1.00
LMNA P02545 5/20 1.00
HTT P42858 5/20 1.00
NPC1 O15118 4/20 1.00
ALDH1A1 P00352 4/20 1.00
NFKB1 P19838 1/20 1.00
NFKB2 Q00653 1/20 1.00
RELA Q04206 1/20 1.00
BLM P54132 4/20 0.75
TDP1 Q9NUW8 4/20 0.75
JAK2 O60674 1/20 0.75
EPHB2 P29323 1/20 0.75
MEN1 O00255 6/20 0.73
KMT2A Q03164 6/20 0.73
CASP3 P42574 4/20 0.73
SENP8 Q96LD8 4/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633257 1.00 MAPT (1.00) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL28408126 0.98 MAPT (0.96) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL7912631 0.89 MAPT (0.80) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL29633300 0.86 CASP3 (0.77) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL14571425 0.86 MAPT (0.77) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL29633237 0.86 RAB9A (1.00) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL16297244 0.86 CASP3 (0.77) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL30991485 0.86 MAPT (0.75) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL16297260 0.86 MAPT (0.75) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1
SCHEMBL30991484 0.86 MAPT (0.75) MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11817554-B2 Supercapacitor based on polymer electrolyte containing Mo(IV) doped hydrogel IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2023-11-14 US claimed
CN-114702400-A 3-trifluoromethylalkenyl-2-phenylamino-1, 4-naphthoquinone compound and preparation method thereof 信阳师范学院 2022-07-05 CN claimed
EP-3856792-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING Ecolab USA, Inc. (US) 2021-08-04 EP claimed
CN-112739725-A Amino quinone anti-polymerization agents and methods of use thereof 埃科莱布美国股份有限公司 2021-04-30 CN claimed
WO-2020068735-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING ECOLAB USA INC. (US) 2020-04-02 WO claimed
US-20200102408-A1 AMINO-QUINONE ANTIPOLYMERANTS AND METHODS OF USING ECOLAB USA INC. 2020-04-02 US claimed
US-20170283374-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA PELLFICURE PHARMACEUTICALS, INC. 2017-10-05 US claimed
EP-3191087-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA Pellficure Pharmaceuticals, Inc. (US) 2017-07-19 EP claimed
WO-2016040896-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA PELLFICURE PHARMACEUTICALS, INC. (US) 2016-03-17 WO claimed
CN-1035057-C Method of preventing polymer scale formation SHINETSU CHEMICAL CO (JP) 1997-06-04 CN claimed
EP-0355575-B1 Method of preventing polymer scale formation SHINETSU CHEMICAL CO (JP) 1994-11-02 EP claimed
US-5298220-A Forming a coating of a solution containing anioic and cationic dyes and water insoluble organonitrogen compound, drying SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-03-29 US claimed
US-5196164-A During addition polymerization, wall coating of anionic dye and cationic dye and organonitrogen compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-03-23 US claimed
CN-1040206-A Prevent to form the method for polymer scale formation SHINETSU CHEMICAL CO (JP) 1990-03-07 CN claimed
EP-0355575-A2 Method of preventing polymer scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1990-02-28 EP claimed
US-20260078248-A1 SIDE-CHAIN FUNCTIONALIZED POLYSTYRENES AS MEMBRANE MATERIALS FOR ALKALINE WATER ELECTROLYZERS, FUEL CELLS AND FLOW BATTERIES FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2026-03-19 US disclosed
EP-4419580-B1 METHOD FOR PROMOTING HYDROSILYLATION REACTION TO PREPARE ESTER-FUNCTIONAL SILOXANE OLIGOMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-27 EP disclosed
CN-1040206-A Prevent to form the method for polymer scale formation SHINETSU CHEMICAL CO (JP) 1990-03-07 CN disclosed
EP-0355575-A2 Method of preventing polymer scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1990-02-28 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170283374-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF PROSTATE CARCINOMA KLK3, ACP3, NR5A1 MAPT 2538/4885SMN1; SMN2 3333/4885RAB9A 3443/4885
US-20260078248-A1 SIDE-CHAIN FUNCTIONALIZED POLYSTYRENES AS MEMBRANE MATERIALS FOR ALKALINE WATER ELECTROLYZERS, FUEL CELLS AND FLOW BATTERIES EPCAM, ENO1, SCNN1G MAPT 3969/4885SMN1; SMN2 2520/4885RAB9A 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.