Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 1/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 1/20 | 1.00 |
| ▸ | RELA | Q04206 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.75 |
| ▸ | JAK2 | O60674 | 1/20 | 0.75 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | CASP3 | P42574 | 4/20 | 0.73 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754259 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL28408126 | 0.98 | MAPT (0.96) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL7912631 | 0.89 | MAPT (0.80) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL16297260 | 0.86 | MAPT (0.75) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL29633300 | 0.86 | CASP3 (0.77) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL29633237 | 0.86 | RAB9A (1.00) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL30991485 | 0.86 | MAPT (0.75) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL16297244 | 0.86 | CASP3 (0.77) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL14571425 | 0.86 | MAPT (0.77) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 | |
| SCHEMBL30991484 | 0.86 | MAPT (0.75) | MAPTSMN1; SMN2RAB9AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702400-A | 3-trifluoromethylalkenyl-2-phenylamino-1, 4-naphthoquinone compound and preparation method thereof | 信阳师范学院 | 2022-07-05 | — | — | CN | claimed |
| CN-118271193-A | Method for promoting catalytic synthesis of 2-amino-1, 4-naphthoquinone compounds by using nicotinic acid as ligand and using dichloro-titanocene | 宁夏师范学院 | 2024-07-02 | — | — | CN | disclosed |
| CN-112739725-B | Amino quinone anti-polymerization agent and method of use thereof | 埃科莱布美国股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| EP-4172165-A1 | PREPARATION OF MULTIFUNCTIONAL ORGANOSILICON COMPOUNDS | Dow Silicones Corporation (US) | 2023-05-03 | — | — | EP | disclosed |
| CN-115052932-A | Composition, method for preparing copolymer and end use of copolymer | 美国陶氏有机硅公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-114702400-A | 3-trifluoromethylalkenyl-2-phenylamino-1, 4-naphthoquinone compound and preparation method thereof | 信阳师范学院 | 2022-07-05 | — | — | CN | disclosed |
| CN-114702400-A | 3-trifluoromethylalkenyl-2-phenylamino-1, 4-naphthoquinone compound and preparation method thereof | 信阳师范学院 | 2022-07-05 | — | — | CN | disclosed |
| CN-114702399-A | 2-trifluoroalkyl-1, 4-naphthoquinone compound and synthetic method thereof | 信阳师范学院 | 2022-07-05 | — | — | CN | disclosed |
| CN-114685295-A | Polyfluoroalkyl-containing 2-amino-1, 4-naphthoquinone compound and preparation method thereof | 信阳师范学院 | 2022-07-01 | — | — | CN | disclosed |
| CN-109748809-B | Method for synthesizing 2-substituted amino-1, 4-naphthoquinone derivative | 中国科学院成都有机化学有限公司 | 2022-05-13 | — | — | CN | disclosed |