Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28931959 | 0.86 | STAT3 (0.59) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28690150 | 0.84 | STAT3 (0.61) | CYP2C9LMNAKMT2AMEN1MAPT | |
| SCHEMBL28691066 | 0.83 | CYP3A4 (0.68) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28699070 | 0.82 | MAPT (0.57) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28681436 | 0.82 | STAT3 (0.61) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL28673390 | 0.81 | MCL1 (0.65) | — | |
| SCHEMBL28680454 | 0.81 | TP53 (0.55) | CYP2C9LMNAKMT2AMEN1MAPT | |
| SCHEMBL28677540 | 0.78 | MEN1 (0.54) | CYP2C9LMNAKMT2AMEN1MAPT | |
| SCHEMBL28695985 | 0.77 | STAT3 (0.55) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL1901939 | 0.76 | CYP2C9 (0.69) | CYP2C9LMNAKMT2AMEN1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113747920-A | Immune checkpoint inhibitor combination therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112703001-A | Combination cancer therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-04-23 | — | — | CN | disclosed |