Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ME2 | P23368 | 1/20 | 0.48 |
| ▸ | ME1 | P48163 | 1/20 | 0.48 |
| ▸ | ME3 | Q16798 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683197 | 0.89 | STAT3 (0.51) | MAPTKMT2AMEN1PAX8GAA | |
| SCHEMBL28931959 | 0.86 | STAT3 (0.59) | MAPTKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL28691066 | 0.84 | CYP3A4 (0.68) | MAPTKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL28677540 | 0.84 | MEN1 (0.54) | MAPTKMT2AMEN1PAX8GAA | |
| SCHEMBL28672666 | 0.82 | CYP2C9 (0.68) | MAPTKMT2AMEN1GAACYP3A4 | |
| SCHEMBL28697036 | 0.82 | MAPT (0.55) | MAPTKMT2AMEN1PAX8GAA | |
| SCHEMBL28690150 | 0.81 | STAT3 (0.61) | MAPTKMT2AMEN1CYP3A4LMNA | |
| SCHEMBL28681436 | 0.79 | STAT3 (0.61) | MAPTKMT2AMEN1GAACYP3A4 | |
| SCHEMBL28680454 | 0.77 | TP53 (0.55) | MAPTKMT2AMEN1GAACYP3A4 | |
| SCHEMBL1900306 | 0.77 | MAPT (0.77) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113747920-A | Immune checkpoint inhibitor combination therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112703001-A | Combination cancer therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-04-23 | — | — | CN | disclosed |