Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.59 |
| ▸ | KLK7 | P49862 | 1/20 | 0.59 |
| ▸ | TACR3 | P29371 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28673422 | 0.89 | MEN1 (0.59) | CYP3A4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28691056 | 0.88 | PLA2G2A (0.53) | CYP3A4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28931959 | 0.87 | STAT3 (0.59) | CYP3A4MEN1KMT2ATACR3KDM4E | |
| SCHEMBL28699070 | 0.84 | MAPT (0.57) | CYP3A4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28672666 | 0.83 | CYP2C9 (0.68) | CYP3A4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28931754 | 0.82 | MEN1 (0.59) | CYP3A4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28690150 | 0.82 | STAT3 (0.61) | CYP3A4MEN1KMT2ATACR3KDM4E | |
| SCHEMBL28696167 | 0.81 | MCL1 (0.55) | CYP3A4MEN1KMT2ATACR3TDP1 | |
| SCHEMBL28681436 | 0.80 | STAT3 (0.61) | CYP3A4MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28680454 | 0.78 | TP53 (0.55) | CYP3A4MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113747920-A | Immune checkpoint inhibitor combination therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112703001-A | Combination cancer therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-04-23 | — | — | CN | disclosed |