Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | FADS1 | O60427 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29898270 | 1.00 | EGFR (0.46) | EGFRGALR3NR2F2TP53PIK3CA | |
| SCHEMBL28690718 | 0.84 | KDR (0.53) | EGFR | |
| SCHEMBL29898311 | 0.84 | KDR (0.53) | EGFR | |
| SCHEMBL28689155 | 0.81 | HPGD (0.47) | EGFRGALR3NR2F2GBA1RAB9A | |
| SCHEMBL29898273 | 0.81 | HPGD (0.47) | EGFRGALR3NR2F2GBA1RAB9A | |
| SCHEMBL11248882 | 0.79 | EGFR (0.52) | EGFRGALR3NR2F2GBA1FADS1 | |
| SCHEMBL28767096 | 0.79 | KDM4E (0.34) | TP53KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28696670 | 0.79 | NR2F2 (0.46) | EGFRGALR3NR2F2TP53GBA1 | |
| SCHEMBL29898285 | 0.79 | NR2F2 (0.46) | EGFRGALR3NR2F2TP53GBA1 | |
| SCHEMBL11261278 | 0.79 | EGFR (0.52) | EGFRGALR3NR2F2TP53GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754636-B | Quinazoline-containing aza-ether compounds | 湖南化工研究院有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-113754636-A | Quinazoline-containing aza-ether compounds | 湖南化工研究院有限公司 | 2021-12-07 | — | — | CN | claimed |