Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | ROS1 | P08922 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256846 | 0.90 | NR2F2 (0.59) | EGFRNR2F2GALR3HTTGBA1 | |
| SCHEMBL11250025 | 0.89 | NPC1 (0.52) | EGFRNR2F2GALR3HTTGBA1 | |
| SCHEMBL11255628 | 0.88 | GBA1 (0.56) | EGFRNR2F2GALR3HTTGBA1 | |
| SCHEMBL11261278 | 0.87 | EGFR (0.52) | EGFRNR2F2GALR3HTTGBA1 | |
| SCHEMBL11246634 | 0.86 | SMN1; SMN2 (0.51) | EGFRNR2F2GALR3HTTGBA1 | |
| SCHEMBL11255510 | 0.84 | GBA1 (0.55) | HTTGBA1NPC1RAB9AKMT2A | |
| SCHEMBL8504539 | 0.82 | EGFR (0.61) | EGFRNR2F2GALR3HTTRAB9A | |
| SCHEMBL11254153 | 0.81 | LDHA (0.61) | EGFRNR2F2GALR3HTTNPC1 | |
| SCHEMBL11240075 | 0.81 | EGFR (0.53) | EGFRNR2F2GALR3HTTGBA1 | |
| SCHEMBL9608140 | 0.80 | EGFR (0.49) | EGFRNR2F2GALR3HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |