SCHEMBL2867334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2866787	0.83	CES2 (0.50)	NPC1SMN1; SMN2LMNAHPGDKDM4E
	SCHEMBL2857712	0.82	CES2 (0.46)	NPC1RAB9ASMN1; SMN2LMNACYP1A2
	SCHEMBL2857587	0.81	NPC1 (0.46)	NPC1RAB9ASMN1; SMN2LMNAPKM
	SCHEMBL14415716	0.79	RAB9A (0.70)	NPC1RAB9ASMN1; SMN2LMNAPKM
	SCHEMBL5520271	0.76	RAB9A (0.61)	NPC1RAB9ASMN1; SMN2LMNAPKM
	SCHEMBL10959090	0.75	MAPT (0.58)	RAB9ASMN1; SMN2LMNACYP1A2CYP2D6
	SCHEMBL2860696	0.75	NPC1 (0.46)	NPC1RAB9ASMN1; SMN2LMNAPKM
	SCHEMBL8806677	0.75	CYP1A2 (0.55)	NPC1RAB9ASMN1; SMN2LMNAPKM
	SCHEMBL15628210	0.75	NPC1 (0.58)	NPC1RAB9ASMN1; SMN2LMNAPKM
	SCHEMBL9958729	0.75	HTT (0.46)	RAB9ASMN1; SMN2LMNACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.