Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.43 |
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.43 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28666353 | 1.00 | ALK (0.45) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| SCHEMBL4566613 | 0.82 | KDR (0.55) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| SCHEMBL28641704 | 0.82 | KDR (0.55) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| SCHEMBL5631936 | 0.76 | KDR (0.62) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| SCHEMBL5630605 | 0.76 | KDR (0.62) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| Malic Acid SCHEMBL28533606 | 0.75 | KDR (0.61) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| Malic Acid SCHEMBL28533602 | 0.75 | KDR (0.61) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| Malic Acid SCHEMBL29904180 | 0.75 | KDR (0.61) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| SCHEMBL28900853 | 0.74 | KDR (0.56) | ALKPRKAA2PRKAA1PDGFRBKDR | |
| SCHEMBL19862519 | 0.72 | KDR (0.67) | ALKPRKAA2PRKAA1PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717159-A | Indolone compounds and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2021-11-30 | — | — | CN | disclosed |