Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.40 |
| ▸ | RXRB | P28702 | 5/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015172 | 0.86 | KDM4E (0.33) | MAPT | |
| SCHEMBL25397077 | 0.78 | TPMT (0.36) | DHODHSMN1; SMN2TP53MAPTALOX15 | |
| SCHEMBL2064910 | 0.77 | KDM4E (0.39) | RXRARXRBRXRGMAPT | |
| SCHEMBL28670662 | 0.72 | RXRB (0.39) | RXRARXRBRXRGMAPT | |
| SCHEMBL25395736 | 0.71 | DHODH (0.35) | RXRARXRBDHODHNPC1PKM | |
| SCHEMBL28665114 | 0.71 | RXRB (0.38) | RXRARXRBRXRGMAPT | |
| SCHEMBL1792650 | 0.69 | RXRA (0.32) | RXRARXRB | |
| SCHEMBL25395982 | 0.67 | KMO (0.51) | RXRARXRBSMN1; SMN2MAPK1TDP1 | |
| SCHEMBL25392198 | 0.67 | EGFR (0.47) | RXRARXRBRXRGTP53HSD17B10 | |
| SCHEMBL3079801 | 0.67 | RXRB (0.72) | RXRARXRBRXRGDHODHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-113831351-A | Novel tetrapyrrole derivatives and application thereof | 上海先辉医药科技有限公司 | 2021-12-24 | — | — | CN | disclosed |