Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | CTSB | P07858 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 5/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | F13A1 | P00488 | 2/20 | 0.47 |
| ▸ | TGM2 | P21980 | 2/20 | 0.47 |
| ▸ | TGM1 | P22735 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675165 | 1.00 | CTSL (0.59) | CTSLCTSBCTSKLTA4HTSHR | |
| SCHEMBL7369799 | 0.86 | CTSL (0.64) | CTSLCTSBCTSKLTA4HTSHR | |
| SCHEMBL28688160 | 0.85 | CTSL (0.55) | CTSLCTSBCTSKLTA4HTSHR | |
| SCHEMBL5692127 | 0.83 | CTSL (0.67) | CTSLCTSBCTSKTSHRALDH1A1 | |
| SCHEMBL2748504 | 0.83 | CTSK (0.58) | CTSLCTSBCTSKLTA4HTSHR | |
| SCHEMBL28249925 | 0.83 | CTSK (0.60) | CTSLCTSBCTSKLTA4HTSHR | |
| SCHEMBL18342444 | 0.83 | CTSL (0.60) | CTSLCTSBCTSKLTA4HTSHR | |
| SCHEMBL18342447 | 0.83 | CTSL (0.60) | CTSLCTSBCTSKLTA4HTSHR | |
| SCHEMBL24261303 | 0.82 | CTSL (0.65) | CTSLCTSBCTSKLTA4HTSHR | |
| SCHEMBL12217282 | 0.82 | CTSL (0.65) | CTSLCTSBCTSKLTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922394-B | 3-tetrazolyl-benzene-1, 2-disulfonamide derivatives as metallo-beta-lactamase inhibitors | 默沙东公司 | 2021-07-13 | — | — | CN | disclosed |