SCHEMBL28675284

SCHEMBL28675284

O=C(O)c1ccc(Oc2ccccc2C(F)C(F)(F)C(F)(F)F)cc1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.46
PYGL P06737 13/20 0.45
PYGM P11217 14/20 0.44
ALDH1A1 P00352 1/20 0.41
HPSE Q9Y251 1/20 0.41
GALK1 P51570 1/20 0.40
CASP6 P55212 1/20 0.40
MCL1 Q07820 1/20 0.40
PLEC Q15149 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6568625 0.83 POLB (0.49) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL4890614 0.79 POLB (0.50) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL28394215 0.79 HPSE (0.47) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL28675286 0.79 POLB (0.47) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL29664286 0.78 POLB (0.65) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL7969637 0.78 POLB (0.65) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL721512 0.76 POLB (0.50) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL28335535 0.76 POLB (0.50) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL28650646 0.76 POLB (0.63) POLBPYGLPYGMALDH1A1HPSE
SCHEMBL6891584 0.75 POLB (0.66) POLBPYGLPYGMALDH1A1HPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107433757-B Endless belt comprising boron nitride nanotubes 施乐公司 2021-10-22 CN disclosed