SCHEMBL28675372

SCHEMBL28675372

[CH2]c1c(C)cc(O)c(C)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
MAPT P10636 4/20 0.40
ALDH1A1 P00352 4/20 0.40
CYP3A4 P08684 3/20 0.40
KDM4E B2RXH2 3/20 0.40
GAA P10253 2/20 0.40
HPGD P15428 2/20 0.40
ALOX15 P16050 2/20 0.40
MAPK1 P28482 2/20 0.40
HIF1A Q16665 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
G6PD P11413 1/20 0.40
CYP2C9 P11712 1/20 0.40
PKM P14618 1/20 0.40
ALOX12 P18054 1/20 0.40
CYP2C19 P33261 1/20 0.40
CCR6 P51684 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31305641 0.75 ACHE (0.50) ACHEMAPTALDH1A1CYP3A4KDM4E
SCHEMBL395710 0.75 CYP3A4 (0.30) CYP3A4MAPK1TSHR
SCHEMBL393790 0.75 ACHE (0.50) ACHEMAPTALDH1A1CYP3A4KDM4E
SCHEMBL2026441 0.72 ACHE (0.48) ACHEMAPTALDH1A1CYP3A4KDM4E
SCHEMBL29372751 0.72 ACHE (0.48) ACHEMAPTALDH1A1CYP3A4KDM4E
SCHEMBL2562811 0.72 ACHE (0.48) ACHEMAPTALDH1A1CYP3A4KDM4E
SCHEMBL28823581 0.72 ACHE (0.48) ACHEMAPTALDH1A1CYP3A4KDM4E
SCHEMBL18109802 0.72 ACHE (0.48) ACHEMAPTALDH1A1CYP3A4KDM4E
SCHEMBL70458 0.72 ACHE (0.48) ACHEMAPTALDH1A1CYP3A4KDM4E
Ethane SCHEMBL27864417 0.72 ACHE (0.48) ACHEMAPTALDH1A1CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed
CN-113785023-A Water-based ink composition for reversible thermal discoloration writing instrument, refill containing the same, and water-based ballpoint pen 株式会社百乐 2021-12-10 CN disclosed