SCHEMBL2026441

SCHEMBL2026441

Cc1cc(O)c(C)c(C)c1-c1c(C)cc(O)c(C)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.48
MAPT P10636 4/20 0.43
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 2/20 0.43
HPGD P15428 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
G6PD P11413 1/20 0.43
CYP2C9 P11712 1/20 0.43
PKM P14618 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP2C19 P33261 1/20 0.43
CCR6 P51684 1/20 0.43
HIF1A Q16665 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2028079 0.90 CYP3A4 (0.42) ACHEMAPTKDM4EALDH1A1CYP3A4
SCHEMBL21002133 0.80 ACHE (0.46) ACHEMAPTKDM4EALDH1A1CYP3A4
SCHEMBL15135054 0.79 TRPA1 (0.42) MAPTKDM4EALDH1A1CYP3A4HPGD
SCHEMBL30388523 0.79 MAPT (0.48) ACHEMAPTKDM4EALDH1A1CYP3A4
SCHEMBL393790 0.79 ACHE (0.50) ACHEMAPTKDM4EALDH1A1CYP3A4
SCHEMBL31305641 0.79 ACHE (0.50) ACHEMAPTKDM4EALDH1A1CYP3A4
SCHEMBL3809941 0.78 SENP1 (0.57) MAPTALDH1A1MEN1KMT2AESR1
SCHEMBL10596945 0.78 KDM4E (0.39) ACHEMAPTKDM4EALDH1A1CYP3A4
SCHEMBL994122 0.77 MAPT (0.46) ACHEMAPTKDM4EALDH1A1CYP3A4
SCHEMBL70458 0.77 ACHE (0.48) ACHEMAPTKDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200375949-A1 BISPHENOL COMPOUNDS TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2020-12-03 US claimed
US-20100208180-A1 Negative Birefringement Polyester Films For LCD AKRON POLYMER SYSTEMS INC. 2010-08-19 US claimed
US-7671167-B2 Poly(arylene ether) copolymer SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-02 US claimed
US-20090247724-A1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-10-01 US claimed
EP-1969030-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2008-09-17 EP claimed
WO-2007067669-A2 POLY (ARYLENE ETHER) COPOLYMER GENERAL ELECTRIC COMPANY (US) 2007-06-14 WO claimed
US-20070135609-A1 Poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2007-06-14 US claimed
US-20070106051-A1 Polyfunctional poly(arylene ether) method CITIBANK, N.A., AS COLLATERAL AGENT 2007-05-10 US claimed
JP-11060681-A None JP disclosed
EP-3636692-B1 POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECH BV (NL) 2026-04-29 EP disclosed
US-12503593-B2 Curable thermosetting composition including poly(arylene ether) copolymer SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-12-23 US disclosed
WO-2025224626-A1 THERMOPLASTIC POLYURETHANE AND ASSOCIATED METHOD AND ARTICLE SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2025-10-30 WO disclosed
EP-3919545-B1 CURABLE THERMOSETTING COMPOSITION INCLUDING POLY(ARYLENE ETHER) COPOLYMER SHPP GLOBAL TECH BV (NL) 2025-10-22 EP disclosed
WO-2025100252-A1 LAMINATE 住友化学株式会社 2025-05-15 WO disclosed
US-5902872-A POLYARYLATE COMPRISING 2,2-BIS/3-METHYL-4-HYDROXYPHENYL/PROPANE UNITS, TEREPHTHALIC ACID UNITS AND ISOPHTHALIC ACID UNITS, HAVING SPECIFIED INHERENT VISCOSITY UNITIKA, LTD. (JP) 1999-05-11 US disclosed
JP-H1160681-A BIPHENOL EPOXY RESIN AND ITS COMPOSITION JSR CORP 1999-03-02 JP disclosed
EP-0884342-A1 Resin for coating formation and method for producing the same UNITIKA LTD. (JP) 1998-12-16 EP disclosed
US-4158027-A BIPHENOL DERIVATIVES USED AS POLYMERIZATION INHIBITORS ICI AMERICAS INC. (US) 1979-06-12 US disclosed
US-4112019-A BISPHENOL POLYMERIZATION INHIBITOR ICI AMERICAS INC. (US) 1978-09-05 US disclosed
US-4049731-A VINYL MONOMERS, BIPHENOL DERIVATIVE AS POLYMERIZATION INHIBITOR ICI UNITED STATES INC. (US) 1977-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200375949-A1 BISPHENOL COMPOUNDS RPP30, RPS10, RPS20 ACHE 4580/4885MAPT 3206/4885KDM4E 846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.