Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282352 | 0.96 | CA12 (0.43) | PLA2G4BCA12CA1CA2CA9 | |
| SCHEMBL31410107 | 0.90 | APP (0.48) | CA12CA1CA2CA9GAA | |
| SCHEMBL21348713 | 0.90 | APP (0.48) | CA12CA1CA2CA9GAA | |
| SCHEMBL29334943 | 0.84 | HDAC1 (0.41) | PLA2G4BCA12CA1CA2CA9 | |
| SCHEMBL656934 | 0.84 | PSEN1 (0.48) | GAAL3MBTL1 | |
| SCHEMBL17940966 | 0.83 | MAPT (0.57) | PLA2G4BGPR119GAAPLA2G4AL3MBTL1 | |
| SCHEMBL7472706 | 0.82 | HDAC8 (0.48) | CA12CA1CA2CA9GAA | |
| SCHEMBL28680418 | 0.82 | MAPT (0.52) | L3MBTL1 | |
| SCHEMBL5637807 | 0.81 | HDAC1 (0.49) | PLA2G4BHDAC1HDAC2L3MBTL1 | |
| SCHEMBL17940960 | 0.81 | MAPT (0.59) | CA1CA2GPR119GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735845-A | Androgen receptor degradation agent and application thereof | 梅德盛 | 2021-12-03 | — | — | CN | disclosed |