Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18282354 | 0.96 | MAPT (0.49) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL21348716 | 0.91 | MAPT (0.52) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL18530427 | 0.91 | MAPT (0.52) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL655716 | 0.85 | PTGS2 (0.60) | MAPTALDH1A1CYP1A2CYP3A4KMT2A | |
| SCHEMBL27238605 | 0.83 | HTR2A (0.46) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL28675412 | 0.82 | PLA2G4B (0.46) | L3MBTL1 | |
| SCHEMBL18282348 | 0.80 | MAPT (0.56) | MAPTL3MBTL1CRHBPCRHR2ALDH1A1 | |
| SCHEMBL28757163 | 0.80 | PTGS2 (0.54) | MAPTALDH1A1CYP1A2CYP3A4KMT2A | |
| SCHEMBL25718431 | 0.79 | KCNH2 (0.54) | MAPTL3MBTL1CRHBPCRHR2HRH3 | |
| SCHEMBL17940966 | 0.79 | MAPT (0.57) | MAPTL3MBTL1KMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735845-A | Androgen receptor degradation agent and application thereof | 梅德盛 | 2021-12-03 | — | — | CN | disclosed |