Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.47 |
| ▸ | CA1 | P00915 | 13/20 | 0.45 |
| ▸ | CA2 | P00918 | 13/20 | 0.45 |
| ▸ | CA12 | O43570 | 11/20 | 0.45 |
| ▸ | CA7 | P43166 | 11/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 11/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12828068 | 0.80 | PNMT (0.50) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL28972016 | 0.76 | PSEN1 (0.40) | CA1CA2CA12CA7CA14 | |
| SCHEMBL24065230 | 0.76 | CA1 (0.71) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL27689519 | 0.75 | PNMT (0.40) | PNMT | |
| SCHEMBL28445305 | 0.75 | PNMT (0.36) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL12828069 | 0.75 | PNMT (0.51) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL13995397 | 0.74 | PNMT (0.53) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL24065052 | 0.74 | PNMT (0.53) | PNMTCA1CA2CA12CA7 | |
| SCHEMBL30685660 | 0.73 | IDO1 (0.54) | CA1CA2 | |
| SCHEMBL28448081 | 0.72 | PNMT (0.43) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710663-A | Modulators of MYC family proto-oncogene proteins | 纳罗医疗公司 | 2021-11-26 | — | — | CN | disclosed |