Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.45 |
| ▸ | TUBB | P07437 | 4/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28694502 | 0.89 | HDAC3 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30543457 | 0.85 | L3MBTL1 (0.42) | ALDH1A1TSHRHDAC3HDAC4HDAC1 | |
| SCHEMBL28694511 | 0.84 | GALR3 (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28931528 | 0.84 | KDM4E (0.44) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28676211 | 0.83 | NT5E (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28681671 | 0.83 | FYN (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28681677 | 0.83 | MAPT (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28681696 | 0.83 | MAPT (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28695292 | 0.81 | NT5E (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30543462 | 0.81 | NT5E (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929635-B | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 沈阳药科大学 | 2023-08-22 | — | — | CN | claimed |
| CN-113929635-A | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 沈阳药科大学 | 2022-01-14 | — | — | CN | claimed |
| CN-113929635-B | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 沈阳药科大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-113929635-A | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 沈阳药科大学 | 2022-01-14 | — | — | CN | disclosed |