Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.42 |
| ▸ | TUBB | P07437 | 3/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543457 | 0.91 | L3MBTL1 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28931528 | 0.90 | KDM4E (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28694511 | 0.90 | GALR3 (0.42) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28675563 | 0.89 | TUBB4A (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30543462 | 0.89 | NT5E (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28695292 | 0.89 | NT5E (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28681677 | 0.89 | MAPT (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28681671 | 0.89 | FYN (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28681696 | 0.89 | MAPT (0.43) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28676211 | 0.89 | NT5E (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929635-B | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 沈阳药科大学 | 2023-08-22 | — | — | CN | claimed |
| CN-113929635-A | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 沈阳药科大学 | 2022-01-14 | — | — | CN | claimed |
| CN-113929635-B | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 沈阳药科大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-113929635-A | 1, 6-diphenyl-1H-benzo [ d ] [1,2,3] triazole compound and preparation method and application thereof | 沈阳药科大学 | 2022-01-14 | — | — | CN | disclosed |