Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.62 |
| ▸ | EHMT2 | Q96KQ7 | 8/20 | 0.54 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441522 | 0.88 | NCF1 (0.65) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22455332 | 0.84 | ENPP1 (0.64) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| Hydrochloric Acid SCHEMBL22441583 | 0.84 | NCF1 (0.67) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22445606 | 0.84 | NCF1 (0.70) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL29357443 | 0.83 | NCF1 (0.68) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22455396 | 0.83 | NCF1 (0.68) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| Hydrochloric Acid SCHEMBL22441576 | 0.81 | NCF1 (0.67) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL20782844 | 0.81 | NCF1 (0.54) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL22445552 | 0.81 | NCF1 (0.65) | NCF1EHMT2EHMT1NPC1PDGFRB | |
| SCHEMBL30446792 | 0.81 | NCF1 (0.65) | NCF1EHMT2EHMT1NPC1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924092-A | Quinoline and quinazoline compounds and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2022-01-11 | — | — | CN | disclosed |