4-Aminophenol

4-Aminophenol

SCHEMBL28675641

CCCCOCC1CO1.Nc1ccc(O)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.63
ALDH1A1 P00352 3/20 0.55
TDP1 Q9NUW8 1/20 0.55
TSHR P16473 3/20 0.47
LTA4H P09960 2/20 0.41
NR5A1 Q13285 1/20 0.41
LMNA P02545 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2C9 P11712 1/20 0.40
PDE4D Q08499 1/20 0.40
ESR1 P03372 4/20 0.39
CYP19A1 P11511 2/20 0.39
ESR2 Q92731 2/20 0.39
CYP2D6 P10635 1/20 0.38
MAPK1 P28482 1/20 0.38
NR1H2 P55055 1/20 0.38
RNASEL Q05823 1/20 0.38
CA3 P07451 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL28118912 0.93 SMN1; SMN2 (0.73) SMN1; SMN2ALDH1A1TDP1TSHRLTA4H
Phenol SCHEMBL2123582 0.85 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1TDP1TSHRLTA4H
4-Aminophenol SCHEMBL5675745 0.85 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1TDP1TSHRLMNA
SCHEMBL10436691 0.82 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1TDP1TSHRLTA4H
Phenol SCHEMBL10598681 0.81 TDP1 (0.66) SMN1; SMN2ALDH1A1TDP1TSHRNR5A1
Phenol SCHEMBL21552429 0.80 TDP1 (0.69) SMN1; SMN2ALDH1A1TDP1TSHRNR5A1
Phenol SCHEMBL1798257 0.80 TDP1 (0.69) SMN1; SMN2ALDH1A1TDP1TSHRNR5A1
SCHEMBL29089 0.79
SCHEMBL7969662 0.79
SCHEMBL2632267 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113784992-A Oxidized aromatic amines and use as antioxidants 埃科莱布美国股份有限公司 2021-12-10 CN disclosed