Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936022 | 0.79 | STK17A (0.48) | STK17BSTK17ACYP1A2SLC29A1LMNA | |
| SCHEMBL14941832 | 0.77 | CYP1A2 (0.44) | STK17BSTK17ACYP1A2SLC29A1JAK2 | |
| SCHEMBL22261163 | 0.74 | JAK3 (0.55) | STK17BSTK17ACYP1A2JAK2JAK1 | |
| SCHEMBL14941801 | 0.71 | PIN1 (0.51) | STK17ACYP1A2LMNATP53MAPT | |
| SCHEMBL28684686 | 0.70 | ALDH1A1 (0.51) | CYP1A2JAK2JAK1TYK2JAK3 | |
| SCHEMBL7939926 | 0.69 | SLC29A1 (0.51) | CYP1A2SLC29A1LMNATP53MAPT | |
| SCHEMBL22261327 | 0.68 | JAK3 (0.56) | STK17BSTK17AJAK2JAK1TYK2 | |
| SCHEMBL30861118 | 0.66 | STK17A (0.48) | STK17BSTK17ACYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL27228324 | 0.66 | STK17A (0.48) | STK17BSTK17ACYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL2148905 | 0.66 | LRRK2 (0.37) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801139-A | Pyrimido-oxazine derivatives as RSK inhibitors and uses thereof | 华东理工大学 | 2021-12-17 | — | — | CN | disclosed |