Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9660243 | 0.91 | CYP3A4 (0.33) | CYP3A4ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL7661042 | 0.91 | DNM1 (0.43) | DNM1CA1CA2LPAR1LPAR3 | |
| SCHEMBL27584519 | 0.82 | — | — | |
| SCHEMBL6141236 | 0.76 | — | — | |
| SCHEMBL7679111 | 0.74 | CYP3A4 (0.34) | CYP3A4ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL29282672 | 0.73 | TSHR (0.42) | CYP3A4ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL6754865 | 0.73 | ADRB2 (0.36) | CYP3A4ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL1682635 | 0.71 | — | — | |
| SCHEMBL9684456 | 0.70 | CYP3A4 (0.31) | CYP3A4ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL29156565 | 0.70 | DNM1 (0.33) | CYP3A4ADRB2ADRB1ADRB3DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652091-B2 | Improved adhesion to rubber surface, wear resistance and surface lubricity | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20060222870-A1 | Coating composition for rubber | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-10-05 | — | — | US | disclosed |