Dipyridyl

Dipyridyl

SCHEMBL28676053

O=c1oc2ccccc2c(O)c1O.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
KDM4E B2RXH2 5/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
MAPT P10636 4/20 0.58
LMNA P02545 3/20 0.58
RECQL P46063 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
HPGD P15428 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALOX12 P18054 1/20 0.53
NQO1 P15559 5/20 0.51
ABCB11 O95342 1/20 0.51
TP53 P04637 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29872 0.85 KDM4E (0.69) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL29379994 0.85 KDM4E (0.69) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL7737431 0.85 KDM4E (0.69) ALDH1A1KDM4EMEN1KMT2AMAPT
Hydrochloric Acid SCHEMBL8701572 0.83 KDM4E (0.67) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL14170199 0.74 MEN1 (1.00) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL28584169 0.73 MEN1 (0.64) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL23727919 0.73 KDM4E (0.62) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL5713261 0.71 KDM4E (0.65) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL29901650 0.70 CA12 (0.73) ALDH1A1KDM4EMEN1KMT2AMAPT
SCHEMBL1648027 0.70 CA12 (0.73) ALDH1A1KDM4EMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717164-B Red fluorescent probe and preparation and application thereof in cell imaging 安徽大学 2022-05-10 CN disclosed
CN-113717164-A Red fluorescent probe and preparation and application thereof in cell imaging 安徽大学 2021-11-30 CN disclosed