Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | NQO1 | P15559 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | TOP1 | P11387 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872 | 0.83 | KDM4E (0.69) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL7737431 | 0.83 | KDM4E (0.69) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL29379994 | 0.83 | KDM4E (0.69) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8701572 | 0.82 | KDM4E (0.67) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL23727919 | 0.78 | KDM4E (0.62) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL11693383 | 0.78 | GAA (0.69) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL669540 | 0.78 | KDM4E (0.62) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL27752675 | 0.78 | KDM4E (0.62) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL5459905 | 0.78 | KDM4E (1.00) | KDM4ENQO1ALDH1A1MEN1KMT2A | |
| SCHEMBL29695571 | 0.78 | KDM4E (1.00) | KDM4ENQO1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148253-B2 | 4-thio coumarins | XTL BIOPHARMACEUTICALS LTD. (IL) | 2006-12-12 | — | — | US | disclosed |
| WO-2005068450-A1 | 4-THIO COUMARINS | VIVOQUEST, INC. (US) | 2005-07-28 | — | — | WO | disclosed |
| US-20040180950-A1 | 4-Thio coumarins | PRESIDIO PHARMACEUTICALS, INC. | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180950-A1 | 4-Thio coumarins | CYP3A4, HAVCR2, CYP4B1 | KDM4E 3748/4885NQO1 307/4885ALDH1A1 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.