SCHEMBL23727919

SCHEMBL23727919

[CH2]c1c(O)c2ccccc2oc1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.62
NQO1 P15559 7/20 0.61
ALDH1A1 P00352 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
LMNA P02545 2/20 0.61
CYP2C9 P11712 2/20 0.61
ABCB11 O95342 1/20 0.61
TP53 P04637 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
TSHR P16473 1/20 0.61
MAPK1 P28482 1/20 0.61
CYP2C19 P33261 1/20 0.61
PDE4D Q08499 1/20 0.61
PCSK7 Q16549 1/20 0.61
GPR35 Q9HC97 1/20 0.61
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
TOP1 P11387 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379994 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL7737431 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL29872 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL11693383 0.81 GAA (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL8701572 0.80 KDM4E (0.67) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL5713261 0.78 KDM4E (0.65) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL29695571 0.77 KDM4E (1.00) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL27752675 0.77 KDM4E (0.62) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL669540 0.77 KDM4E (0.62) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL5459905 0.77 KDM4E (1.00) KDM4ENQO1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US disclosed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO disclosed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO disclosed
CN-1950353-B Materials and methods for treating coagulation disorders ARYX THERAPEUTICS 2011-06-01 CN disclosed
CN-1950353-A Materials and methods for treating coagulation disorders ARYX THERAPEUTICS (US) 2007-04-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB KDM4E 4637/4885NQO1 234/4885ALDH1A1 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.