SCHEMBL28676366

SCHEMBL28676366

CO[Si](OC)(OC(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
KCNN4 O15554 4/20 0.34
KIF11 P52732 1/20 0.34
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 1/20 0.33
CES1 P23141 1/20 0.32
POLB P06746 1/20 0.31
CYP19A1 P11511 1/20 0.31
NR1H2 P55055 2/20 0.31
NR1H3 Q13133 2/20 0.31
TSHR P16473 2/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28236304 0.84 IDO1 (0.35) MAPK1KIF11ALDH1A1TSHR
SCHEMBL10707324 0.79 MAPK1 (0.33) MAPK1ALDH1A1ALOX15POLBTSHR
SCHEMBL28198895 0.79 NR1H2 (0.36) MAPK1ALDH1A1POLBNR1H2NR1H3
SCHEMBL37986 0.78 CA4 (0.41) MAPK1ALDH1A1POLBTSHRCA4
SCHEMBL28172888 0.78 POLB (0.32) MAPK1ALDH1A1POLBCA4
SCHEMBL393508 0.78 POLB (0.32) MAPK1ALDH1A1POLBTSHRCA4
SCHEMBL28928050 0.77 KIF11 (0.41) MAPK1KCNN4KIF11
Water SCHEMBL18606224 0.75 POLB (0.39) MAPK1ALDH1A1POLBTSHRCA4
Ammonia Solution, Strong SCHEMBL2330946 0.75 POLB (0.39) MAPK1ALDH1A1POLBTSHRCA4
SCHEMBL1974068 0.75 CA1 (0.41) MAPK1ALDH1A1POLBTSHRCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106566207-A PBT material applied to cover plate and seat ring of toilet bowl and preparation method of PBT material 厦门集优新材料有限公司 2017-04-19 CN claimed
CN-113906153-A Barrier film, laminate and packaging product 大日本印刷株式会社 2022-01-07 CN disclosed
CN-105717747-B Photosensitive resin composition and application thereof 奇美实业股份有限公司 2021-12-21 CN disclosed
CN-105717743-B Photosensitive resin composition and application thereof 奇美实业股份有限公司 2021-12-21 CN disclosed
CN-111886131-A Barrier resin film, barrier laminate, and packaging material using barrier laminate 大日本印刷株式会社 2020-11-03 CN disclosed
CN-106566207-A PBT material applied to cover plate and seat ring of toilet bowl and preparation method of PBT material 厦门集优新材料有限公司 2017-04-19 CN disclosed