Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676366 | 0.84 | MAPK1 (0.35) | TSHRKIF11ALDH1A1MAPK1 | |
| SCHEMBL5587008 | 0.84 | TSHR (0.43) | IDO1AGXTTSHRMAOBALDH1A1 | |
| SCHEMBL17391584 | 0.84 | TSHR (0.43) | IDO1AGXTTSHRMAOBALDH1A1 | |
| SCHEMBL17391615 | 0.76 | TSHR (0.50) | IDO1AGXTTSHRMAOBALDH1A1 | |
| SCHEMBL28928050 | 0.73 | KIF11 (0.41) | KIF11MAPK1 | |
| SCHEMBL4369027 | 0.71 | MAPK1 (0.32) | ALDH1A1MAPK1 | |
| SCHEMBL28900359 | 0.70 | ALDH1A1 (0.40) | IDO1AGXTTSHRMAOBALDH1A1 | |
| SCHEMBL8637212 | 0.70 | TSHR (0.40) | IDO1AGXTTSHRMAOBALDH1A1 | |
| SCHEMBL28872334 | 0.70 | AGXT (0.43) | IDO1AGXTTSHRMAOBALDH1A1 | |
| SCHEMBL29104811 | 0.68 | ESR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108441115-B | Room-temperature-cured radiation-resistant silicone resin composition and preparation method thereof | 山东省科学院新材料研究所 | 2020-02-14 | — | — | CN | claimed |
| CN-108441115-A | A kind of room temperature curing radiation resistance silicon resin composition and preparation method thereof | 山东省科学院新材料研究所 | 2018-08-24 | — | — | CN | claimed |
| CN-108441115-B | Room-temperature-cured radiation-resistant silicone resin composition and preparation method thereof | 山东省科学院新材料研究所 | 2020-02-14 | — | — | CN | disclosed |
| CN-108441115-A | A kind of room temperature curing radiation resistance silicon resin composition and preparation method thereof | 山东省科学院新材料研究所 | 2018-08-24 | — | — | CN | disclosed |