Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326030 | 0.81 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1GAASMN1; SMN2F2 | |
| SCHEMBL21801447 | 0.80 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1GAASMN1; SMN2F2 | |
| SCHEMBL1732930 | 0.78 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1GAASMN1; SMN2F2 | |
| SCHEMBL9326634 | 0.77 | JAK2 (0.46) | L3MBTL1ALDH1A1F2TSHRMAPT | |
| SCHEMBL28677153 | 0.77 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1GAASMN1; SMN2F2 | |
| SCHEMBL9324812 | 0.76 | NPSR1 (0.47) | L3MBTL1ALDH1A1GAASMN1; SMN2F2 | |
| SCHEMBL12806428 | 0.75 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1GAASMN1; SMN2F2 | |
| SCHEMBL7769409 | 0.72 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1GAASMN1; SMN2F2 | |
| SCHEMBL9326908 | 0.72 | MEN1 (0.50) | L3MBTL1SMN1; SMN2F2TSHRMAPT | |
| SCHEMBL425129 | 0.72 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1GAASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082367-A1 | TRIAZOLE DERIVATIVE OR A SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1995243-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082367-A1 | TRIAZOLE DERIVATIVE OR A SALT THEREOF | HSD11B1, HSD11B2, HSD17B1 | L3MBTL1 1809/4885ALDH1A1 389/4885GAA 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.